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Adaptive Strategies for Clinical Evolution and Novel Dynamics in Colorectal Cancer

ASCEND-CRC

Personalize Treatment: Quickly identifying and applying the most effective therapeutic approach for each patient.
Adapt in Real Time: Standardizing biomarker discovery and developing dynamic treatment strategies that can adapt in real-time to tumor evolution.
Revolutionize Clinical Trials: Significantly accelerating the development and implementation of targeted therapies.
In 2024, ARPA-H launched the ADAPT program, investing $142 million to improve how we treat advanced cancers. ASCEND-CRC program is one of three ADAPT trials, focusing on metastatic colorectal cancer and aiming to:

OUR MISSION:
Advancing Cancer Research

transforming

250

300

23.1M

PATIENTS
FIRST PHASE

PATIENTS
SECOND PHASE

IN GRANT FUNDING

ARPA-H-logo-full-color-padding-01 1

FUNDED AND SUPPORTED BY

713-792-2828
ascend@mdanderson.org
1515 Holcombe Blvd
Unit 426
Houston, TX 77030

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